They can interact with other substances, and too much can be harmful. Chromium picolinate interferes with the absorption of thyroid medications. Thyroid medication should be taken at least 3 to 4 hours before or after any chromium supplement.
Supplemental chromium can interact with antacids, corticosteroids, H2 blockers, proton pump inhibitors, beta-blockers , insulin , nicotinic acid, non-steroidal anti-inflammatory drugs NSAIDs , and prostaglandin inhibitors. People who are using any of these drugs, and those with diabetes should speak to their doctor before taking chromium supplements, as these could affect the action of their regular medications.
Chromium supplements should not be taken during pregnancy or while breastfeeding, and they should not be given to children. Studies repeatedly show that isolating nutrients in supplement form will not provide the same health benefits as consuming the nutrient from a whole food. It is not an individual nutrient that makes certain foods an important part of our diet, but how nutrients work together.
Chromium deficiency is rare, and studies have not yet confirmed the benefits of taking supplements, so it is best to obtain chromium through food. There have been no reported cases of chromium poisoning due to food intake, so the IOM has not fixed a maximum intake level. However, large doses of chromium in supplement form can cause stomach problems, low blood sugar, and kidney or liver damage. It is always safer to get required nutrients from foods sources and to discuss any use of supplements with a physician.
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Use precise geolocation data. Select personalised content. Create a personalised content profile. Measure ad performance. Select basic ads. Create a personalised ads profile. Select personalised ads. Apply market research to generate audience insights. Measure content performance. Develop and improve products. List of Partners vendors. Chromium is a mineral that humans require in trace amounts.
It's found in small quantities in meat, whole grains, some fruits and vegetables, and spices. In , chromium was first identified as an element that enables the hormone insulin to function properly. Since then, chromium has been studied for diabetes and has become a popular dietary supplement. It is widely available in health food stores, drug stores and online. Chromium is believed to help the body process carbohydrates and fats. One form, chromium picolinate, is popular because it is one of the more easily absorbed forms.
Research on the benefits of chromium to enhance fat loss and increase performance in bodybuilders and athletes has provided mixed results. The best designed studies have not found benefit of chromium supplementation on body composition or loss of weight and fat.
Chromium picolinate is also used in the treatment of diabetes and depression. Antioxidant effects of chromium supplementation with type 2 diabetes mellitus and euglycemic subjects. J Agric Food Chem. Nutraceuticals in diabetes and metabolic syndrome. Cardiovasc Ther. Effects of over-the-counter drugs on 51chromium retention and urinary excretion in rats. Nutr Res. Effects of acute chromium supplementation on postprandial metabolism in healthy young men. Chromium supplementation does not improve glucose tolerance, insulin sensitivity, or lipid profile: a randomized, placebo-controlled, double-blind trial of supplementation in subjects with impaired glucose tolerance.
Effects of chromium supplementation on plasma lipids, apolipoproteins, and glucose in elderly subjects. Chromium in metabolic and cardiovascular disease. Horm Metab Res. Chromium picolinate does not improve key features of metabolic syndrome in obese nondiabetic adults.
Metab Syndr Relat Disord. Effect of chromium niacinate and chromium picolinate supplementation on lipid peroxidation, TNF-alpha, IL-6, CRP, glycated hemoglobin, triglycerides, and cholesterol levels in blood of streptozotocin-treated diabetic rats.
Free Radic Bio Med. Effects of chromium brewer's yeast supplementation on body mass, blood carbohydrates, and lipids and minerals in Type 2 diabetic patients. Biol Trace Elem Res. The effect of chromium picolinate on muscular strength an body composition in women athletes.
J Strength Cond Res. Chromium supplementation and resistance training: effects on body composition, strength, and trace element status of men. Am J Clin Nut. McCarty MF. Complementary measures for promoting insulin sensitivity in skeletal muscle.
Med Hypotheses. Anabolic effects of insulin on bone suggests a role for chromium picolinate in preservation of bone density. Chromium picolinate may favorably influence the vascular risk associated with smoking by combating cortisol-induced insulin resistance.
Chromium supplementation in overweight and obesity: a systematic review and meta-analysis of randomized clinical trials. Obes Rev.
Chromium: friend or foe? Arch Family Med. The effect of chromium picolinate on serum cholesterol and apolipoprotein fractions in human subjects. West J Med. Comparative effects of chromium, vanadium and gymnema sylfestre on sugar-induced blood pressure elevations in SHR. Influence of chromium-enriched yeast on blood glucose and insulin variables, blood lipids, and markers of oxidative stress in subjects with type 2 diabetes mellitus.
Ravina A, Slezack L. Chromium in the treatment of clinical diabetes mellitus. Reversal of corticosteroid-induced diabetes mellitus with supplemental chromium. Diabetic Med. Chromium as adjunctive treatment for type 2 diabetes. Ann Pharmacother. Follow the instructions on your product label carefully. Most people will get all the chromium they need from the foods they eat. The best way to get your daily requirement of chromium is to eat a well-balanced diet.
Though evidence to support its use is lacking, some people take chromium picolinate to improve athletic performance, help certain mental health disorders, or treat other conditions. Health Topics. Health Tools. Chromium Picolinate CRM. Reviewed: November 19, Side Effects. Stop using chromium picolinate and call your doctor at once if you have: thinking problems, trouble concentrating; problems with balance or coordination; or liver problems --nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice yellowing of the skin or eyes.
Common side effects may include: headache; sleep problems insomnia ; or mood changes, feeling irritable. Check your blood sugar carefully if you are diabetic. Store at room temperature away from moisture and heat.
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