Antiherpetic Activity of L-Lysine-alpha-oxidase in different dosage forms. Antibiot Khimioter. Success of L-lysine therapy in frequently recurrent Herpes simplex infection.
Treatment and prophylaxis. Use of lysine in treating recurrent oral Herpes simplex infections. Gen Dent. A multicentered study of lysine therapy in Herpes simplex infection. Lysine prophylaxis in recurrent Herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol. Relation of arginine-lysine antagonism to Herpes simplex growth in tissue culture. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis.
The objective of this study was to show, through clinical observation, a significant effect on the annual incidence reduction of recurrent herpes in a 8-year follow up. The prospective study was conducted in a group of 12 individuals, being five males and seven females aged between 30 and 48 years old, suffering from recurrent herpes labialis lesions with manifestations ranging from over one or more episode per month to one or more every three months.
All members belonged to the same socio-economic and cultural class and they had never received any systemic therapy prior to the study. Regarding the topical treatment, antiviral acyclovir cream were used three times a day since the first signal of the lesion. Before starting treatment with L-Lysine, data were collected retrospectively from the last 12 months on the number of occurrences of lesions as well as the healing time of each lesion.
The traced data were pooled to be compared. The treatment was initiated with L-Lysine, manipulated in a single homoeopathic pharmacy, during the lesion crust phase using one capsule of mg daily for 30 days, taken fasting with water, one hour before a meal or two hours minimum after.
Patients were instructed to continue the use of the same acyclovir cream they were using prior to Lysine keeping a record of herpes episodes and their healing time within a year.
The group was contacted every 2 months during the first year and data were collected. Patients were instructed on how to control the triggering factors such as sun exposure and stress and dietary advice with a diet rich in L-Lysine as well as avoiding the consumption of foods rich in Arginine was prescribed. Monitoring was continued in the following years every 4 months and a data sheet with the number of annual injuries was completed.
All the statistical procedures were performed using GraphPad Prism version 6. Since the first year using L-Lysine, all the patients informed a decrease of number of recurrent herpes labialis. The data showed that the annual number of injuries were similar in men and women Table 1. Some patients presented improvement in the occurrence of herpes with low intensity lesions compared to those of the outbreaks before the Lysine, as they also reported that many lesions did not evolve to the bullous phase disappearing even in the prodromal phase.
All small demonstrations occurred due to unprotected excessive solar radiation, either for long periods of stress or after a large intake of peanuts. The results of the evaluations are demonstrated in Table 1 and figure 3 , considering the mean and standard deviation of lesions in a period of 8 years. Figure 3 Graphical representation of annual incidence of injuries before and after L-Lysine cycle - 8-years follow up.
L-Lysine has the function, amongst others, of tissue repairing, since it stimulates growth while participating in the hormones synthesis. Consequently, there was also a reduction of actions required during subsequent years of monitoring when there had been lysine supplementation for 30 days a year. United States US English. Submit an Idea. Brand Logo. All rights reserved. Terms Of Use. Privacy Policy. About Our Ads. Children's Privacy Policy.
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Learn more about our commitment to oral health education. Badge field New. Published date field. Top Articles. What Is Lysine? Other Cold Sore Treatment Options While it's uncertain whether taking an oral lysine supplement or using a cream containing lysine could provide the results you may be looking for, it's worth noting that you have many other cold sore treatment options.
Lysine is normally well tolerated at recommended dosages, but higher dosages may have more risks of the following side effects. The most common side effects of Lysine supplementation are diarrhea, cramps, abdominal pain, and nausea.
If you are prone to kidney or gallstone issues, consult with your doctor before starting Lysine supplementation. There are no reported interactions between taking Lysine with a prescription cold sore treatment like Valacyclovir. If your cold sore breakouts are frequent and intense, you may benefit from speaking with a doctor about prescription anti-viral medications like Valacyclovir generic Valtrex. You can have an Online Visit with our doctors today to see if Valacyclovir treatment is a good option for your cold sore breakouts - maybe along with some additional Lysine.
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