How does 2 3 bpg affect hemoglobin

Photos of 2,3-Bisphosphoglycerate. Videos on 2,3-Bisphosphoglycerate. Cochrane Collaboration on 2,3-Bisphosphoglycerate. Bandolier on 2,3-Bisphosphoglycerate. TRIP on 2,3-Bisphosphoglycerate.

Ongoing Trials on 2,3-Bisphosphoglycerate at Clinical Trials. Trial results on 2,3-Bisphosphoglycerate. Clinical Trials on 2,3-Bisphosphoglycerate at Google. FDA on 2,3-Bisphosphoglycerate. CDC on 2,3-Bisphosphoglycerate. Books on 2,3-Bisphosphoglycerate.

Be alerted to news on 2,3-Bisphosphoglycerate. News trends on 2,3-Bisphosphoglycerate. Blogs on 2,3-Bisphosphoglycerate. Definitions of 2,3-Bisphosphoglycerate. Patient resources on 2,3-Bisphosphoglycerate. Discussion groups on 2,3-Bisphosphoglycerate. Patient Handouts on 2,3-Bisphosphoglycerate. Directions to Hospitals Treating 2,3-Bisphosphoglycerate.

Risk calculators and risk factors for 2,3-Bisphosphoglycerate. Symptoms of 2,3-Bisphosphoglycerate. Diagnostic studies for 2,3-Bisphosphoglycerate. Treatment of 2,3-Bisphosphoglycerate. CME Programs on 2,3-Bisphosphoglycerate. Patents on 2,3-Bisphosphoglycerate. List of terms related to 2,3-Bisphosphoglycerate. Editor-In-Chief: C. The ease with which haemoglobin releases oxygen to the tissues is controlled by erythrocytic 2,3-diphosphoglycerate 2,3-DPG such that an increase in the concentration of 2,3-DPG decreases oxygen affinity and vice versa.

This review article describes the synthesis and breakdown of 2,3-DPG in the Embden-Meyerof pathway in red cells and briefly explains the molecular basis for its effect on oxygen affinity. Interaction of the effects of pH, Pco2, temperature and 2,3-DPG on the oxyhaemoglobin dissociation curve are discussed.

The role of 2,3-DPG in the intraerythrocytic adaptation to various types of hypoxaemia is described. The increased oxygen affinity of blood stored in acid-citrate-dextrose ACD solution has been shown to be due to the decrease in the concentration of 2,3-DPG which occurs during storage.

Methods of maintaining the concentration of 2,3-DPG in stored blood are described. The clinical implication of transfusion of elderly people, anaemic or pregnant patients with ACD stored blood to anaesthetically and surgically acceptable haemoglobin concentrations are discussed.